It would be great to have a way to host apps that are deployed in multiple regions, so the app is fast anywhere in the world. I guess this is quite a challenge, because you might also need a multi-region distributed database. But it would be great to have an easy way of building such an app without the dev-ops overhead.

For financial services products (UK is a FinTech hub) many agreements require that data be located within the UK.

For application with primarily Indian users, it makes much more sense to allow hosting apps in a Indian region.

Need to support clients who require Canada-domiciled data storage/processing

show some love for the south americans :D